WebJun 1, 2008 · RNA dynamics: it is about time. Many recently discovered RNA functions rely on highly complex multistep conformational transitions that occur in response to an array of cellular signals. These dynamics accompany and guide, for example, RNA cotranscriptional folding, ligand sensing and signaling, site-specific catalysis in … WebSep 26, 2013 · RNA conformation plays a major role in processes such as transcription termination, RNA processing and translation initiation. Hence, the folding of RNA is an important determinant in regulation of gene expression in many cellular systems, in both prokaryotes and eukaryotes.

RNA Folding - an overview ScienceDirect Topics

WebThe evidence showing that the self-assembly of complex RNAs occurs in discrete transitions, each relating to the folding of sub-systems of increasing size and … WebHow does RNA fold? We are now developing a quantitative and predictive framework for RNA folding kinetics and thermodynamics. We have developed a “Reconstitution … siemem thicker from medication

RNA Folding — Herschlag Lab

WebJun 10, 2024 · In addition to clarifying RNA folding and its roles in cellular processes, an ensemble perspective of RNA structure is required to understand how some mutations, including potentially disease ... WebAbstract Recent advances in interrogating RNA folding dynamics have shown the classical model of RNA folding to be incomplete. Here, we pose three prominent questions for the field that are at the forefront of our understanding of the importance of RNA folding dynamics for RNA function. siemence workexpro