Germacrene synthase
WebJan 7, 2024 · Background: The sesquiterpene germacrene A is a direct precursor of ß-elemene that is a major component of the Chinese medicinal herb Curcuma wenyujin … Web'Germacrene-A synthase' published in 'Class 4–6 Lyases, Isomerases, Ligases' Keywords. Escherichia Coli; Molecular Weight; Catalytic Activity; Functional Analysis
Germacrene synthase
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WebMay 1, 2002 · de Kraker et al. (1998, 2001, 2002) showed that the sesquiterpene lactones in chicory and probably also in a large number of other plant species originate from a common germacrane precursor, (+)-germacrene A.The biosynthesis of this sesquiterpene olefin from the ubiquitous sesquiterpene precursor farnesyl diphosphate (FDP) is catalyzed by a (+) … WebApr 30, 2024 · As expected, purified geosmin synthase yielded the sesquiterpenoids geosmin, germacradienol and germacrene D in the assay mixture upon incubation with FPP (S2 Fig and S3 Fig), whereas the monoterpene limonene was formed when GPP was added to limonene synthase containing crude extracts (S4 Fig and S5 Fig).
WebMay 1, 2002 · de Kraker et al. (1998, 2001, 2002) showed that the sesquiterpene lactones in chicory and probably also in a large number of other plant species originate from a … WebJul 1, 2006 · The N-part of geosmin synthase catalyzes the cyclization FPP to germacradienol and germacrene D the C-part catalyzes cyclization and fragmentation of germacradienol into geosmin (Giglio et al ...
WebDec 17, 2015 · Germacrene A synthase (GAS) from Solidago canadensis catalyzes the conversion of farnesyl diphosphate (FDP) to the plant sesquiterpene (+)-germacrene A. After diphosphate expulsion, farnesyl cation reacts with the distal 10,11-double bond to afford germacrene A (>96%) and 2% α-humulene, which arises from 1,11-cyclization of … WebJul 28, 2012 · A putative gene encoding germacrene D synthase (GenBank Accession No. JQ247185) from tea plant (Camellia sinensis) was isolated by rapid amplification of …
WebThe enzyme germacrene-A synthase (EC 4.2.3.23) catalyzes the chemical reaction (2 E ,6 E )-farnesyl diphosphate ⇌ {\displaystyle \rightleftharpoons } (+)-( R )-gemacrene A + …
WebDec 15, 2004 · Two new sesquiterpene synthase cDNAs, designated Sc11 and Sc19, have been isolated from goldenrod and functional expression in Escherichia coli identified Sc11 as (+)-germacrene D synthase and Sc19 as (-)-germacrene D synthase. Thus, the enantiomers of germacrene D are the products of separate, but closely related (85% … the nurse coachesWebJan 7, 2024 · The sesquiterpene germacrene A is a direct precursor of ß-elemene that is a major component of the Chinese medicinal herb Curcuma wenyujin with prominent … the nurse coachWebGermacrene D Receptor Neurons. One type of receptor neurons, tuned to the sesquiterpene germacrene D, frequently occurred in recordings from heliothine moths, … michigan scechs required for grad coursesWebSep 20, 2012 · Highlights This manuscript is firstly characterized for germacrene A synthase gene in Citrus species. The gene identification of mono- or sesqui-terpene could not be estimated from nucleotide sequence and enzymatic characterization is indispensable. The information of transcriptional data and gene function is valuable to consider bio … michigan scenic routeWeb(+)-Germacrene D synthase (EC 4.2.3.77) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((+)-germacrene-D-forming). This enzyme catalyses the following chemical reaction the nurse collectiveWebApr 1, 1999 · Formation of (-)-germacrene D involves a stereospecific 1,3-hydride shift of H-1si of farnesyl diphosphate. Both products are formed from a common intermediate. The enzyme mediates a key step in the biosynthesis of geosmin (see EC 4.1.99.16), a widely occurring metabolite of many streptomycetes, bacteria and fungi. michigan schech creditsWebMar 3, 1998 · The germacrene synthase activity expressed from clone pLE11.3 exceeded the limonene synthase activity by a factor of 10, when measured in the same enzyme … michigan schedule amd 2020