Rubrerythrins

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August undefined, 2024

WebbHigh-resolution crystal structures of Desulfovibrio vulgaris nigerythrin (DvNgr), a member of the rubrerythrin (Rbr) family, demonstrate an approximately 2-Å movement of one iron (Fe1) of the diiron site from a carboxylate to a histidine ligand upon conversion of the mixed-valent ([Fe2(II),Fe1(III)]) to diferrous states, even at cryogenic temperatures. WebbThis review compares the features of the different Ferritins and considers how they, and other members of the Ferritin-like superfamily, have evolved. It also considers relevant features of the eleven other known families within the Ferritin-like superfamily, particularly the highly diverse rubrerythrins.

High-resolution crystal structures of Desulfovibrio vulgaris ...

WebbDesulforubrerythrin from Campylobacter jejuni holds recently been biochemical and spectroscopically characterized. It is an member von the rubrerythrin family, and it is composed of three structural domains: the N-terminal desulforedoxin division with one non-heme iron center, followed by a four-helix bundl … Webb9.2.4 Dps Proteins and Rubrerythrins 313 9.2.5 The Mineral Core 319 9.2.6 Haemosiderins 319 9.3 Iron Uptake and Release from Ferritin 320 9.3.1 Iron Uptake in Ferritins 320 9.3.1.1 Entry of Fe(II) into the Protein Shell 321 9.3.1.2 Oxidation of Fe2+ by Ferroxidase Sites 323 9.3.1.3 Mineralisation of the Iron Core 325 blechgummi

The Ferritin-like superfamily: Evolution of the biological …

WebbThese results are consistent with a superoxide reductase rather than SOD activity of Rbo and with a peroxidase activity of Rbr. A joint role for Rbo and Rbr as a novel cytoplasmic … Webbspecificityunexpectedly provided the first structure of the oxi-dized active site (15). In this structure (Fig. 1A), the distance betweenthetwoironsisshorter,at3.2Å,anda -oxobridge Webb6 jan. 2024 · As a next-generation probiotic, Clostridium tyrobutyricum, which is considered obligate anaerobe, has been extensively considered a promising candidate for future use to promote health benefits.The industrial applications were limited by its weak tolerance to oxygen stress during fermentation. Here, we enhanced the oxidative stress tolerance of … blech hagen

Desaturases:EmergingModels forUnderstandingFunctional Diversificationof …

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Webbplural of rubrerythrin ... Definition from Wiktionary, the free dictionary WebbThe National Agricultural Library is one of four national libraries of the United States, with locations in Beltsville, Maryland and Washington, D.C. blech halleWebbThe rubrerythrins served as key peroxidases under anoxic conditions. However, they quickly lost activity upon aeration, and AhpCF and catalase were induced to compensate. The AhpCF is an NADH peroxidase that effectively degraded low micromolar levels of H2O2, while the catalytic cycle of catalase enabled it to quickly degrade higher … fran mccaffery age

"Webb19 aug. 2011 · Like rubrerythrins, symerythrin contains a π-helical segment in helix C (πC) adjacent to the metallocenter. In addition, as predicted, 6 a π-helical segment (πA) is present in helix A of symerythrin (Fig. 2b). Each of these two π-helices has a Pro at its C-terminal end (Fig 2a) and is associated with a ~20° kink in its core helix. " - Rubrerythrins

Rubrerythrins

The Ferritin-like superfamily: Evolution of the biological …

Webb8 sep. 2024 · Tolerance of C. difficile to low O2 tensions requires the presence of the alternative sigma factor, σB, involved in the general stress response. Among the genes positively controlled by σB, four encode proteins likely involved in O2 detoxification: two flavodiiron proteins (FdpA and FdpF) and two reverse rubrerythrins (revRbr1 and revRbr2). Webb16 feb. 1999 · Here we demonstrate that rubrerythrin and nigerythrin from Desulfovibrio vulgaris and rubrerythrin from Clostridium perfringens show NADH peroxidase activities …

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WebbÀ propos. Actuellement post-doctorant dans le laboratoire de Patrick Viollier au sein du département de Microbiologie et de Médecine Moléculaire de l'université de Genève, j'étudie les régulations post-transcriptionnelles chez Caulobacter crescentus. Auparavant, Attaché Temporaire d'Enseignement et de Recherche (ATER) à l'université ... Webb25 apr. 2002 · Rubrerythrins are non-haem iron proteins that have been implicated in oxidative stress protection in anaerobic bacteria and archaea. However, up to now, this …

Webb25 apr. 2002 · Purified rubrerythrins from other organisms have been shown to catalyse reduction of hydrogen peroxide, while showing relatively sluggish reaction with dioxygen and little or no catalase or superoxide dismutase activities. Porphyromonas gingivalis contains a superoxide dismutase but lacks catalase and haem peroxidases. WebbBackground: The Ferritins are part of the extensive 'Ferritin-like superfamily' which have diverse functions but are linked by the presence of a common four-helical bundle …

WebbFormat: Hypertext Plain Text mFasta Compact Hypertext Compact Text. Row Display: up to 5 up to 10 All 38 rows. Color Bits: 0.5 bit 1.0 bit 1.5 bit 2.0 bit 2.5 bit 3.0 bit 3.5 bit 4.0 bit … WebbIn contrast to this, we identified upregulation of glutaredoxin, thioredoxin family/like proteins, rubrerythrins, peroxiredoxins, peroxidase, alkyl hydroperoxidase, type A flavoproteins, FeS cluster assembly protein, and cysteine desulfurases, indicating the genomic potential of "Ca.

WebbRubrerythrins are non-haem iron proteins that have been implicated in oxidative stress protection in anaerobic bacteria and archaea. However, up to now, this role has not been …

Webb1 sep. 2004 · Rubrerythrins are characterized by a unique combination of a non-sulfur, oxo-bridged diiron site similar to that of ferritin in the N-terminal and a rubredoxin-like FeS 4 … fran martin hal linden\\u0027s wifeWebboptimale Temperatur (60--75~C, j e naeh Verbindung) und optimaler pH-Wert (6 N HC1). Die Potentialkurve ist der mV-Aehse am _~quivalenzpunkt fast parallel, das _~quivalenzpotentialE~K E liegt bei allen Verbindungenzwisehen 60 und 90 mV. Als Elektrodensystem dient eine gl~nzende Platinelektrode und eine ges~tt. … fran mccaffery brian ferentzWebb14 okt. 2011 · Rubrerythrins are diiron-containing peroxidases that belong to the ferritin-like superfamily (FLSF). Here, we describe the structures of symerythrin, a novel … fran mccaffery bioWebb5 nov. 1991 · The complete polypeptide chain of rubrerythrin from the sulfate reducing bacterium Desulfovibrio vulgaris, strain Hildenborough NCIB 8303, was found by protein chemical techniques to consist of 191 residues and to have the amino acid sequence [sequence: see text] The C-terminal part of the protein (position 153—-191) shows the … fran mccaffery contract pdfWebbHeme iron and nonheme dimanganese catalases protect biological systems against oxidative damage caused by hydrogen peroxide. Rubrerythrins are ferritine-like nonheme diiron proteins, which are structurally and mechanistically distinct from the heme-type catalase but similar to a dimanganese KatB enzyme. In order to gain more insight into … fran mccaffery chairWebb7 feb. 2006 · A total of four genes encoding rubrerythrins are present in the genome of C. acetobutylicum (Nölling et al. 2001). Two normal rubrerythrin genes are positioned at … fran mccaffery contract extension fran mccaffery children ages